The 15th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies (CLEFT2025) will be held at Kyoto International Conference Hall (Kyoto, Japan) from October 20 to 24, 2025. The theme of the conference is "Best time in Kyoto to create cleft history!” Cleft palate treatment requires the collaboration of medical professionals and researchers from various fields. The conference is attended by medical professionals and researchers from more than 120 countries around the world, and each meeting generates lively discussions and international exchanges. To "deepen multidisciplinary and international collaboration," our goal is to "make history in cleft palate treatment" in Kyoto, Japan.