Cytokines are critical factors in tumorigenesis, metastasis, and the therapeutic response. They promote or counteract malignant transformation and growth of cancer cells through cell autonomous effects on cell proliferation, survival and motility. Furthermore, cytokines are key factors in cellular communication in the tumor microenvironment and have major roles in inflammation, angiogenesis, stromagenesis and anti-tumor immunity. This Aegean conference on cytokine signaling in cancer aims to bring together outstanding experts in fundamental and translational cytokine research to foster collaboration and knowledge in understanding cancer etiology, pathogenesis, and response to immunotherapies, along with devising novel cytokine-specific diagnostic approaches and treatment modalities.
Themes/topics that will be focused on are:
Cytokines and intercellular communications Cytokines and senescence One Health: Comparative aspects & other diseases Protumorigenic cytokines Immune-Related Adverse Events (irAEs) Inflammation and cancer Tumor microenvironment Synthetic biology and therapeutic approaches